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LabTurbo 48
Full Automated DNA/RNA extraction System
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LabTurbo 48

Full Automated DNA/RNA Extraction System


LabTurbo 48 Compact System can fully automate DNA / RNA extraction of up to 48 samples in 90 minutes from raw sample (auto – sampling) to nucleic acid elution in an unibody of (W x D x H) 66 x 64 x 160 cm. The sample size can be loaded up to 2 ml for serum/plasma, whole blood, and urine; up to 0.5 ml buffy coat; or up to 100 mg tissues. The elution volume can be collected as less as 60 µl. It can effectively purify cellular, viral, bacterial, tissue, and circulation DNA / RNA from a broad variety of samples such as blood, blood cells, buffy coat, cultured cells, plasma, serum, culture medium, urine, sputum, stool, vaginal swab, forensic samples, fixed tissue (FFPE), plant ,fish, or food products. The performances of LabTurbo 48C are excellent on DNA / RNA recovery, purity, sensitivity, and cross-contamination prevention.

No. of Samples Sample Volumes Technology Processing Barcode Reading Pipette PCR Setup
1 – 48 Input up to 2 ml
Elute down to 50 µl
Membrane Column / Vacuum ~ 90 mins Included 6 1 – 48
Fast Extraction in Compact Size
Up to 48 samples can be processed in 90 minutes. The DNA/RNA extraction from raw sample to nucleic acid elute is within a compact body of (W x D x H) 66 x 64 x 160 cm.
Large Sample Size
Large sample amount of up to 2 ml can be processed and small elution volume can be collected as low as 60 µl.
Large Throughput
By continuous operation with five units, up to one thousand samples can be processed in regular working hours every day.
Easy- to-Use, All-in-One system
Prevents human errors, saves time and labor, barcode documentation for sample and reagent tracking, auto-aliquoting from primary tube, automatic reagent import, 6-strip format for rapid worktable setup, auto-cleaning functions, and liquid handling (PCR setup).
Various Applications
This system is suitable for clinical, agricultural, research and forensic fields. Whole blood / buffy coat, human/animal/plant tissue, cultured cells, bacteria, forensic samples (swab, etc), body fluid (serum/plasma, etc), and samples which are difficult to handle such as sputum, FFPE and stool can be processed.
Guaranteed Result
Performance guaranteed for DNA/RNA recovery, purity, sensitivity, reproducibility, and cross-contamination free by using innovative membrane column vacuum technology.
Whole Blood
Whole Blood (µl) Yields (µg) Concentration (ng/µl) Purity (A260/A280)
220 3 ~ 8 15 ~ 40 1.7 ~ 1.9
500 6 ~ 15 30 ~ 75 1.7 ~ 1.9
1000 15 ~ 45 75 ~ 225 1.7 ~ 1.9
2000 35 ~ 100 175 ~ 500 1.7 ~ 1.9
HBV Serum
Identical samples were extracted by LabTurbo and B brand. Here we can see the better performance of LabTurbo (Higher HBV copies detected). Also, LabTurbo showed no cross-contamination, good consistency and good linearity.
(1 to 48 sample numbers indicates the sample position of LabTurbo extraction)
HCV Serum
Identical samples were extracted by  LabTurbo and B brand. Here we can see the better performance of LabTurbo (Higher HCV copies detected). Also, LabTurbo showed no cross-contamination, good consistency and good linearity.
(1 to 48 sample numbers indicates the sample position of LabTurbo extraction)
DNA
Sample Yields (mg) Concentration (ng/µl) Purity (A260/A280)
Rice leaf (20 mg) 4 ~ 8 20 ~ 40 1.7 ~ 1.9
Oil palm leaf (50 mg) 1.5 ~ 4.5 15 ~ 45 1.7 ~ 1.9
RNA
Sample Yields (mg) Concentration (ng/µl) Purity (A260/A280)
Arabidopsis leaf (100 mg) 30 ~ 45 300 ~ 450 1.9 ~ 2.1
Chicken liver (10 mg) 10 ~ 20 100 ~ 200 1.9 ~ 2.1
Mouse liver(10 mg) 20 ~ 40 200 ~ 400 1.9 ~ 2.1
Mouse femur (10 mg) 15 ~ 30 150 ~ 300 1.9 ~ 2.1
Mouse tibia (10 mg) 15 ~ 25 150 ~ 250 1.9 ~ 2.1
Mouse heart (15 mg) 10 ~ 25 100 ~ 250 1.9 ~ 2.1
Mouse muscle (15 mg) 5 ~ 15 50 ~ 150 1.9 ~ 2.1
Forensic
It is a very tedious and laborious work to pre-lyse and transfer the lysate to automation tubes for forensic samples. However, those works are no longer needed with LabTurbo. LabTurbo is an all-in-one system. Solid forensic samples can be directly loaded without pre-lysis and additional transfer. Nothing is left for labor. LabTurbo works for all kinds of forensic samples.
Sample Amount of Reaction Yields (ng/µl)
Cigarette butts Cut 1 cm filter tip, take 1/2 ~ 0.9
Straw Cut 1 cm straw, take 1/2 ~ 0.12
Blood Swab(30 mL) With blood taken at about 0.5 cm2 ~ 18
Saliva Swab With saliva taken at about 0.5 cm2 ~ 21
Blood stain With blood taken at about 0.5 cm2 ~ 0.6
What are the advantages of using LabTurbo for Forensic Sample Extraction?
No pretreatment needed
Put solid forensic samples directly into sample tubes with the sample plugs and apply them to LabTurbo for direct automated nucleic acid extraction.
Extract different samples at the same time
Different kinds of forensic samples can be processed at the same time. It is not necessary for sample sorting and it is not needed to use different extraction protocols for different kinds of forensic samples. All the samples can be processed at the same time.
Sample-mixing during the interval of lysis incubation
It is a big challenge to get maximal yields of DNA products from forensic samples. The mixing functions during the interval of the long-time lysis incubation is necessary for this challenge. Nothing is left for labor. LabTurbo provides such functions to completely address this challenge and get maximal yields of DNA products.
Type
Floor stand ( Plug and Play)
Size
  • 66 cm (W) X 64cm (D) X 160 cm (H)
  • 26 inch (W) X 25 inch (D) X 62.4 inch (H)
Throughput
1- up to 48 samples
Sample Volume
Up to 2.0 ml
Elution Volume
30 to 200 µl
Processing time
  • 0.22 ml sample in 90 mins(48 samples)
  • 0.5 ml sample in 120 mins (48 samples)
  • 1.0 ml sample in 150 mins(48 samples)
  • 2.0 ml sample in 150 mins (24 samples)
Pipette
  • 6 pipette channels
  • Volume range: 3 – 1000 µl
  • Precision: CV<5%
Feature
  • Barcode for sample and eluate tracking
  • Documentation
  • Auto-sample transfer from primary tube
  • Worktable setup check
  • Auto-reagent arranging , filling and cleaning
  • Diverse sample types
  • Auto worktable recovery
  • Easy maintenance
  • Liquid handling (PCR Setup)
Working unit
  • 12" Touch panel PC/Windows XP
  • Barcode reader(1D)
  • Pause door with reagent reservoirs(5)
  • Real time Camera
  • UV light
  • Robotic unit:
    1. 6-channel pipette spanning 9-18 mm
    2. Gripper
    3. Object detector
    4. Ultrasonic detector
  • Worktable unit:
    1. 96-well tip rack(3)
    2. Elution buffer(CCEB) thermal rack
    3. Primary tube rack tray
    4. Sample lysis thermal block
    5. Tube rack(Proteinase K/IC/Master Mix)
    6. Binding-washing vacuum manifold
    7. Reagent tanks(5)
    8. Elution vacuum manifold
    9. Tip re-use rack
    10. Waste vent
  • Auto-reagent arranging , filling and cleaning unit
  • Vacuum pump (air flow 120-140 L/min)
  • Waste bottle (5L) x 1
  • Accessories(optional):
    1. Barcode reader(2D)
    2. P-rack for primary tube
    3. P-rack black adapter(41 mm) for primary tube
    4. P-rack silver adapter(35 mm) for primary tube
    5. D-rack for screw tube(D tube)
    6. 96 well PCR tube/plate adapter
Power requirement
110 / 220 V, 50-60 Hz
Operation condition
15-30 °C
Regulatory
In compliance with CE standards
File Name Explanation Tpye Upload Date Download
LabTurbo 48-Compact user manual pdf 2014-09-09


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